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Faculty > Faculty By Research Interest > Phyllis Huettner, MD

Professor, Pathology and Immunology
Professor, Obstetrics and Gynecology
Section Head, Ob/Gyn Pathology
Section Head of Surgical Pathology
Room 300S, Peters Building
Office: (314) 362-0118
E-mail: huettner@wustl.edu
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Research

My research interests are focused on gynecologic and obstetrical disorders. I am interested in determining what role histologic features, immunohistochemical markers and molecular markers play in the classification and prediction of behavior of various lesions. My most recent work involves loss of heterozygosity in cervical cancer. I am interested in determining how specific chromosomal losses relate to prognosis and to established histo-pathologic prognostic factors.

Service to the Department

PresentSection Head, Gynecologic Pathology
PresentQuality Assurance for Surgical Pathology
PresentSupervisor of Pathologists Assistants
PresentMember, Resident Selection Committee
PresentPathology Representative to Gynecologic Oncology Group

Service to the University

PresentSections Head, OB-Gyn Pathology portion of Second Year Pathology Course
PresentCourse Director, OB-Gyn Pathology Clerkship

Diagnostic Expertise

Placental pathology and relationship to obstetrical and neonatal conditions
Gynecologic malignancies

Clinical Interest

Anatomic and Molecular Pathology - Gynecological Pathology

Selected Publications

Buttin BM, Powell MA, Mutch DG, Rader JS, Herzog TJ, Gibb RK, Huettner P, Edmonston TB, Goodfellow P. Increased risk for HNPCC-associated synchronous and metachronous malignancies in patients with MSI-positive endometrial carcinoma lacking MLH1 promoter methylation.. Clin Cancer Res 10:481-490, 2004 Abstract

Buttin BM, Powell MA, Mutch DG, Babb SA, Huettner PC, Edmonston TB, Herzog TJ, Rader JS, Gibb RK, Wh. Penetrance and expressivity of MSH6 germline mutations in seven kindreds not ascertained by family history.. Am J Hum Genet 74:1262-1269, 2004 Abstract

Wright JD, Powell MA, Mutch DG, Rader JS, Gibb RK, Huettner PC, Herzog TJ. Synchronous ovarian metastatses at the time of laparotomy for colon cancer.. Gynecol Oncol 92:851-855, 2004 Abstract

Ylagan LR, Dehner LP, Huettner PC, Lu D. Columnar cell variant of papillary thyroid carcinoma: cytologic findings in a case with review of the literature. Acta Cytol 48:73-77, 2004 Abstract

Li J, Gerhard DS, Zhang Z, Huettner PC, Wright J, Nguyen L, Lu D, Rader JS. Detecting and typing genital human papillomavirus using denaturing high-performance liquid chromatography. J Clin Microbiol 41:5563-5571, 2003 Abstract

Wright JD, Powell MA, Rader JS, Pfeifer JD, Huettner PC, Merritt DF. Acute abdominal pain with a calcified pelvic mass. J Pediatr Adolesc Gynceol 16:237-241, 2003 Abstract

Lee EY, Heiken JP, Huettner PC. Late recurrence of malignant melanoma presenting as peritoneal carcinomatosis.. Abdom Imaging 28:284-286, 2003 Abstract

Wright JD, Powell MA, Horowitz NS, Huettner PC, White F, Herzog TJ. Placental site trophoblastic tumor presenting with a pneumothorax during pregnancy. Int J Gynecol Pathol 21:224-230, 2002 Abstract

Nucci MR, O'Connell JT, Huettner PC, Cviko A, Sun D, Quade BJ. H-Caldesmon expression effectively distinguishes endometrial stromal from uterine smooth muscle tumors.. Am J Surg Pathol 25:455-463, 2001 Abstract

O Sullivan MJ, Rader JS, Gerhard DS, Li Y, Trinkaus KM, Gersell DJ, Huettner PC. Loss of heterozygosity at 11q23.3 in vasculoinvasive and metastatic squamous cell carcinoma of the cervix.. Hum Pathol 32:475-478, 2001 Abstract

Rader JS, Li Y, Huettner PC, Xu Z, Gerhard DS. Cervical cancer suppressor gene is within 1 cM on 6p23.. Genes Chromosomes Cancer 27:373-379, 2000 Abstract

Neuman RJ, Huettner PC, Li L, Mardis ER, Duffy BF, Wilson R, Rader JS. Association between DQB1 and cervical cancer in patients with human papilloma virus and family controls. Obstet Gynecol 95:134-140, 2000 Abstract

Bernardo BD, Huettner PC, Merritt DF, Ratts VS. Idiopathic calcinosis cutis presenting as labial lesions in children: report of two cases with literature review. J Pediatr Adolesc Gynecol 12:157-160, 1999 Abstract

Pfeifer JD, Odem RR, Huettner PC.. Menstrual abnormalities in a premenopausal woman with endometrial malacoplakia. Obstet Gynecol 93:839, 1999 Abstract

Pickhardt PJ, Fisher AJ, Balfe DM, Dehner LP, Huettner PC. Desmoplastic small round cell tumor of the abdomen: radiologic-histopathologic correlation. Radiology 210:633-638, 1999 Abstract

Huettner PC, Gerhard DS, Gersell DJ. Loss of heterozygosity in stage I cervical cancer: comparison with histopathologic and clinical prognostic factors.. Human Pathol 29:364-370, 1998 Abstract

Rader JS, Gerhard DS, O'Sullivan MJ, Li Y, Li l, Liapis H, Huettner PC. Cervical intraepithelial neoplasia III shows frequent alleleic loss in 3p and 6p. Genes Chromosomes Cancer 22:57-65, 1998 Abstract

Rader JS, Kamarasova T, Huettner PC, Li L, Li Y, Gerhard DS. Allelotyping of all chromosomal arms in invasive cervical cancer.. Oncogene 13:2737-2741, 1996 Abstract